Use of the loop diuretic torsemide in three dogs with advanced heart failure

J Vet Cardiol. 2011 Dec;13(4):287-92. doi: 10.1016/j.jvc.2011.10.001. Epub 2011 Oct 24.

Abstract

Diuretics are a mainstay of therapy in dogs with heart failure. In dogs with advanced heart failure, moderate to high doses of loop diuretics such as furosemide are used with diminishing effects as profound activation of neuroendocrine systems promote signs of congestive heart failure. The loop diuretic torsemide has several characteristics that make it suitable for treatment of advanced heart failure including longer half-life, increased potency of diuretic action, and anti-aldosterone effects. This case report details the administration of torsemide in 3 dogs with advanced heart failure and apparent furosemide resistance.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Diuretics / therapeutic use*
  • Dog Diseases / drug therapy*
  • Dogs
  • Euthanasia, Animal
  • Fatal Outcome
  • Female
  • Furosemide / therapeutic use
  • Heart Failure / drug therapy
  • Heart Failure / veterinary*
  • Male
  • Sodium Potassium Chloride Symporter Inhibitors / therapeutic use*
  • Sulfonamides / therapeutic use*
  • Torsemide

Substances

  • Diuretics
  • Sodium Potassium Chloride Symporter Inhibitors
  • Sulfonamides
  • Furosemide
  • Torsemide