Surgical management of sinonasal hemangiopericytomas: a case series

Head Neck. 2012 Oct;34(10):1492-6. doi: 10.1002/hed.21926. Epub 2011 Oct 22.

Abstract

Background: Sinonasal hemangiopericytomas are rare low-grade sarcomas. The role of endoscopic management has not been adequately studied.

Methods: This study was conducted through retrospective medical chart review of patients seen with sinonasal hemangiopericytomas at 2 institutions over a 19-year period. Demographic, clinicopathological, and surgical information was analyzed with descriptive statistics.

Results: Thirteen patients with a diagnosis of sinonasal hemangiopericytomas were treated. The most common symptoms were obstruction (69%) and epistaxis (35%). All tumors were localized in the nasal cavity, and half had extension to 1 or more sinuses. Resection was performed endoscopically in 6 patients. Median intraoperative blood loss was 500 mL; median operative time was 165 minutes. Two patients received postoperative radiation. There were no recurrences with a median follow-up of 25 months. Three patients presented with recurrences, 2 local and 1 distant, up to 13 years after primary tumor removal.

Conclusion: Surgery for sinonasal hemangiopericytomas can be challenging; both endoscopic and open approaches may be used to treat these highly vascular tumors.

Publication types

  • Comparative Study
  • Multicenter Study

MeSH terms

  • Adult
  • Aged
  • Biopsy, Needle
  • Cohort Studies
  • Endoscopy / methods
  • Female
  • Follow-Up Studies
  • Hemangiopericytoma / diagnosis
  • Hemangiopericytoma / pathology*
  • Hemangiopericytoma / surgery*
  • Humans
  • Immunohistochemistry
  • Length of Stay
  • Magnetic Resonance Imaging / methods
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / pathology*
  • Neoplasm Recurrence, Local / surgery
  • Paranasal Sinus Neoplasms / diagnosis
  • Paranasal Sinus Neoplasms / pathology*
  • Paranasal Sinus Neoplasms / surgery*
  • Rare Diseases
  • Registries
  • Retrospective Studies
  • Risk Assessment
  • Tomography, X-Ray Computed / methods
  • Treatment Outcome