Design and characterization of a metal ion-imidazole self-assembled monolayer for reversible immobilization of histidine-tagged peptides

Chem Commun (Camb). 2011 Dec 7;47(45):12391-3. doi: 10.1039/c1cc15510e. Epub 2011 Oct 21.

Abstract

We report the design and characterization of a metal ion-imidazole self-assembled monolayer on a gold electrode. The resultant monolayer is well-suited for direct immobilization of histidine and methylene blue-modified peptides.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Electrochemical Techniques
  • Electrodes
  • Gold / chemistry
  • Histidine / chemistry*
  • Imidazoles / chemistry*
  • Immobilized Proteins / chemistry
  • Ions / chemistry
  • Metals / chemistry*
  • Methylene Blue / chemistry
  • Oligopeptides / chemistry*
  • Peptides / chemistry*

Substances

  • His-His-His-His-His-His
  • Imidazoles
  • Immobilized Proteins
  • Ions
  • Metals
  • Oligopeptides
  • Peptides
  • Histidine
  • Gold
  • imidazole
  • Methylene Blue