BOP-mediated one-pot synthesis of C5-symmetric macrocyclic pyridone pentamers

Chem Commun (Camb). 2011 Dec 14;47(46):12488-90. doi: 10.1039/c1cc14377h. Epub 2011 Oct 21.

Abstract

We report here, for the first time, the BOP-mediated one-pot macrocyclization that is facilitated and guided by internally placed intramolecular H-bonds to allow for the highly selective formation of five-residue cation-binding macrocycles.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chemistry Techniques, Synthetic / methods*
  • Macrocyclic Compounds / chemical synthesis*
  • Macrocyclic Compounds / chemistry*
  • Models, Molecular
  • Molecular Conformation
  • Organophosphorus Compounds / chemistry*
  • Polymers / chemical synthesis*
  • Polymers / chemistry*
  • Pyridones / chemistry*

Substances

  • Macrocyclic Compounds
  • Organophosphorus Compounds
  • Polymers
  • Pyridones
  • benzotriazol-1-yloxy-tris(dimethylamino)phosphonium