Abstract
Premature birth often is associated with neurodevelopmental disabilities. In this issue of Science Translational Medicine, a pair of papers investigate--in patients and in a reliable animal model--the effects of glucocorticoids on cerebellar development after premature birth.
MeSH terms
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Animals
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Brain Injuries / drug therapy*
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Cerebellum / drug effects*
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Cerebellum / growth & development*
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Cerebellum / injuries*
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Cyclohexylamines / therapeutic use*
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Female
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Glucocorticoids / adverse effects*
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Hedgehog Proteins / agonists*
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Humans
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Male
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Receptors, G-Protein-Coupled / agonists*
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Smoothened Receptor
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Thiophenes / therapeutic use*
Substances
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Cyclohexylamines
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Glucocorticoids
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Hedgehog Proteins
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Receptors, G-Protein-Coupled
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SAG compound
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Shh protein, mouse
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Smo protein, mouse
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Smoothened Receptor
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Thiophenes