Death cap (Amanita plalloides) poisonings are still a great diagnostic and therapeutic problem in Poland. Despite of regular educational activity, the Poles are confusing toxic mushrooms with edible ones. Death cap is mainly a cause of accidental poisoning, although suicidal intoxications also occur. This study presents some authors'observations which were made during diagnosing and treatment of patients hospitalized in Poznan Department of Toxicology in 2010 year. The circumstances of poisonings, kind of symptoms and time when they developed, the main biochemical abnormalities are shown. The way of treatment with N-acetylcysteine and silibinin is discussed.