Three new steroidal saponins from Fritillaria pallidiflora

J Asian Nat Prod Res. 2011 Oct;13(11):1014-22. doi: 10.1080/10286020.2011.619979. Epub 2011 Oct 19.

Abstract

Three new steroidal saponins, pallidiflosides A (1), B (2), and C (3), have been isolated from the dry bulbs of Fritillaria pallidiflora Schrenk. Their structures were elucidated as 26-O-β-d-glucopyranosyl-(25R)-furost-5,20(22)-dien-3β,26-diol-3-O-β-d-xylopyranosyl(1 → 4)-[α-l-rhamnopyranosyl(1 → 2)]-β-d-glucopyranoside (1); 26-O-β-d-glucopyranosyl-3β,26-dihydroxyl-20,22-seco-25(R)-furost-5-en-20,22-dione-3-O-α-l-rhamnopyranosyl(1 → 2)-β-d-glucopyranoside (2); and (25R)-spirost-5-ene-3β,17α-diol-3-O-β-d-glucopyranosyl(1 → 4)-β-d-galactopyranoside (3) by spectroscopic techniques and chemical means.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / isolation & purification*
  • Fritillaria / chemistry*
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Plant Roots / chemistry
  • Saponins / chemistry
  • Saponins / isolation & purification*
  • Stereoisomerism
  • Steroids / chemistry
  • Steroids / isolation & purification*

Substances

  • Drugs, Chinese Herbal
  • Saponins
  • Steroids
  • pallidifloside A
  • pallidifloside B
  • pallidifloside C