Nocodazole is a high-affinity ligand for the cancer-related kinases ABL, c-KIT, BRAF, and MEK

ChemMedChem. 2012 Jan 2;7(1):53-6. doi: 10.1002/cmdc.201100410. Epub 2011 Oct 14.

Authors

Hwangseo Park¹, Seunghee Hong, Sungwoo Hong

Affiliation

¹ Department of Bioscience and Biotechnology, Sejong University, Seoul, Korea. hspark@sejong.ac.kr

PMID: 22002881
DOI: 10.1002/cmdc.201100410

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antineoplastic Agents / pharmacology*
Humans
Mitogen-Activated Protein Kinase Kinases / antagonists & inhibitors*
Mitogen-Activated Protein Kinase Kinases / metabolism
Models, Molecular
Neoplasms / drug therapy
Neoplasms / enzymology*
Nocodazole / pharmacology*
Proto-Oncogene Proteins B-raf / antagonists & inhibitors*
Proto-Oncogene Proteins B-raf / metabolism
Proto-Oncogene Proteins c-abl / antagonists & inhibitors*
Proto-Oncogene Proteins c-abl / metabolism
Proto-Oncogene Proteins c-kit / antagonists & inhibitors*
Proto-Oncogene Proteins c-kit / metabolism

Substances

Antineoplastic Agents
Proto-Oncogene Proteins c-kit
Proto-Oncogene Proteins c-abl
Proto-Oncogene Proteins B-raf
Mitogen-Activated Protein Kinase Kinases
Nocodazole