Abstract
Background:
The association of HIV and myeloma has rarely been reported in the literature. This following case discusses the presentation of acute kidney injury (AKI) in a 53-year-old lady with HIV, subsequently diagnosed with myeloma. Furthermore, we describe recovery of renal function and dialysis independence using a combination of light chain removal by dialysis with a high cut-off dialyzer and chemotherapy.
Investigations:
Physical examination, urine, blood tests, renal biopsy, bone marrow aspirate and trephine, US scan.
Diagnosis:
Myeloma.
Management:
Dialysis and chemotherapy.
MeSH terms
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Acute Kidney Injury / blood
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Acute Kidney Injury / etiology*
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Acute Kidney Injury / therapy*
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Antineoplastic Agents / therapeutic use
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Biomarkers, Tumor / blood
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Female
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HIV Seropositivity / blood
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HIV Seropositivity / complications*
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Humans
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Immunoglobulin Light Chains / blood*
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Kidney Neoplasms / blood
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Kidney Neoplasms / complications*
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Kidney Neoplasms / drug therapy
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Middle Aged
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Multiple Myeloma / blood
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Multiple Myeloma / complications*
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Multiple Myeloma / drug therapy
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Recovery of Function
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Renal Dialysis*
Substances
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Antineoplastic Agents
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Biomarkers, Tumor
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Immunoglobulin Light Chains