Antimicrobial ointments and methicillin-resistant Staphylococcus aureus USA300

Emerg Infect Dis. 2011 Oct;17(10):1917-20. doi: 10.3201/eid1710.101365.

Abstract

We tested 259 methicillin-resistant Staphylococcus aureus isolates and 2 USA300 ATCC type strains for susceptibility to bacitracin and neomycin contained in over-the-counter antibacterial ointments. Resistance to both bacitracin and neomycin was found only in USA300. The use of over-the counter antimicrobial drugs may select for the USA300 clone.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / pharmacology*
  • Bacitracin / pharmacology
  • Humans
  • Methicillin-Resistant Staphylococcus aureus / drug effects*
  • Methicillin-Resistant Staphylococcus aureus / genetics
  • Methicillin-Resistant Staphylococcus aureus / isolation & purification
  • Microbial Sensitivity Tests
  • Neomycin / pharmacology
  • Nonprescription Drugs / administration & dosage
  • Nonprescription Drugs / pharmacology*
  • Ointments
  • Polymyxin B / pharmacology

Substances

  • Anti-Bacterial Agents
  • Nonprescription Drugs
  • Ointments
  • Bacitracin
  • Neomycin
  • Polymyxin B