Psychotripine: a new trimeric pyrroloindoline derivative from Psychotria pilifera

Org Lett. 2011 Nov 4;13(21):5896-9. doi: 10.1021/ol202536b. Epub 2011 Oct 14.

Abstract

Psychotripine, a trimeric pyrroloindoline derivative with an unprecedented hendecacyclic system bearing a hexahydro-1,3,5-triazine unit, was isolated from the leaves of Psychotria pilifera. The structure was elucidated on the basis of spectroscopic and quantum theory. A possible biogenesis was also postulated.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Line, Tumor
  • Cell Survival / drug effects
  • Humans
  • Indoles / chemistry*
  • Indoles / pharmacology
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Plant Leaves / chemistry
  • Psychotria / chemistry*
  • Pyrroles / chemistry*
  • Pyrroles / pharmacology
  • Quantum Theory

Substances

  • Indoles
  • Pyrroles
  • psychotripine