Abstract
We highlight the detection of a rare vanM genotype in Enterococcus faecium. This isolate exhibited a VanB phenotype, with high levels of resistance to vancomycin (MIC, >256 mg/liter) and susceptibility to teicoplanin (MIC, 1 mg/liter). It was, however, vanB negative by PCR. Further screening for other van loci revealed the presence of a complete vanM operon.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / pharmacology
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DNA, Bacterial / chemistry
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DNA, Bacterial / genetics
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Enterococcus faecium / drug effects*
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Enterococcus faecium / genetics*
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Enterococcus faecium / isolation & purification
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Female
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Genotype
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Gram-Positive Bacterial Infections / microbiology*
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Hospitals
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Humans
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Microbial Sensitivity Tests
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Middle Aged
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Molecular Sequence Data
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Phenotype
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Sequence Analysis, DNA
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Teicoplanin / pharmacology
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Vancomycin / pharmacology
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Vancomycin Resistance*
Substances
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Anti-Bacterial Agents
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DNA, Bacterial
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Teicoplanin
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Vancomycin