Abstract
Aplasia cutis congenita (ACC) is a congenital defect consisting of a circumscribed absence of skin that usually involves the scalp. The etiology is uncertain, and several teratogenic agents such as methimazole have been involved. We report two cases of ACC and other anomalies in newborns exposed to methimazole during pregnancy.
© 2011 Wiley Periodicals, Inc.
MeSH terms
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Adult
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Antithyroid Agents / adverse effects*
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Ectodermal Dysplasia / chemically induced*
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Female
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Graves Disease / drug therapy*
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Humans
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Infant, Newborn
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Male
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Methimazole / adverse effects*
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Pregnancy
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Prenatal Exposure Delayed Effects / chemically induced*
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Propylthiouracil / adverse effects
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Scalp / abnormalities
Substances
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Antithyroid Agents
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Methimazole
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Propylthiouracil