Actin in herpesvirus infection

Viruses. 2011 Apr;3(4):336-46. doi: 10.3390/v3040336. Epub 2011 Apr 12.

Abstract

Actin is important for a variety of cellular processes, including uptake of extracellular material and intracellular transport. Several emerging lines of evidence indicate that herpesviruses exploit actin and actin-associated myosin motors for viral entry, intranuclear transport of capsids, and virion egress. The goal of this review is to explore these processes and to highlight potential future directions for this area of research.

Keywords: Rho GTPase; actin; herpes; myosin.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Actins / genetics
  • Actins / metabolism*
  • Animals
  • Cytoskeleton / genetics
  • Cytoskeleton / metabolism
  • Cytoskeleton / virology
  • Herpesviridae / genetics
  • Herpesviridae / physiology*
  • Herpesviridae Infections / genetics
  • Herpesviridae Infections / metabolism*
  • Herpesviridae Infections / virology
  • Humans
  • Myosins / genetics
  • Myosins / metabolism
  • Virus Replication

Substances

  • Actins
  • Myosins