Objective: To review the mechanism of improved revascularization of free fat grafting with adipose-derived stem cells (ADSCs).
Methods: The literature related to the basic researches of ADSCs in free fat grafting and angiogenesis was reviewed.
Results: Angiogenesis is a sequence process in time and space which is regulated by various factors. ADSCs possess the capability of secreting many angiogenic growth factors and differentiating into various lineages.
Conclusion: ADSCs affect every process of angiogenesis with clear improved angiogenic effects, however, the mechanisms of angiogenic effects need the further researches.