[Diagnostic laparoscopy under dual antiplatelet therapy with clopidogrel and aspirin]

Med Klin Intensivmed Notfmed. 2011 Sep;106(1):48-51. doi: 10.1007/s00063-011-0026-5. Epub 2011 Oct 7.
[Article in German]

Abstract

Dual antiplatelet therapy using aspirin and a thienopyridine (e.g. clopidogrel) is known to be essential in patients in whom percutaneous coronary intervention with stent implantation has been performed in order to prevent stent thrombosis and its fatal consequences. On the other hand dual antiplatelet therapy increases the incidence of perioperative bleeding complications. In case of urgent or emergency surgery the risk of perioperative stent thrombosis on the one hand and the perioperative bleeding risk on the other has to be evaluated carefully in order to keep time period without sufficient platelet inhibition as short as possible. The presented case offers a strategy for managing perioperative administration of antiplatelet agents.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Angioplasty, Balloon, Coronary
  • Aspirin / administration & dosage
  • Aspirin / adverse effects*
  • Clopidogrel
  • Diagnosis, Differential
  • Drug Substitution
  • Drug Therapy, Combination
  • Drug-Eluting Stents
  • Eptifibatide
  • Female
  • Humans
  • Laparoscopy*
  • Multiple Myeloma / diagnosis
  • Peptides / administration & dosage
  • Peptides / adverse effects
  • Platelet Aggregation Inhibitors / administration & dosage
  • Platelet Aggregation Inhibitors / adverse effects*
  • Postoperative Hemorrhage / chemically induced*
  • Risk Factors
  • Thrombosis / prevention & control
  • Ticlopidine / administration & dosage
  • Ticlopidine / adverse effects
  • Ticlopidine / analogs & derivatives*

Substances

  • Peptides
  • Platelet Aggregation Inhibitors
  • Clopidogrel
  • Eptifibatide
  • Ticlopidine
  • Aspirin