The articles related with combination of Back-shu and Front-mu points searched in CNKI and Pubmed databases during the past 10 years were studied. The conclusions indicate that the application of combination of Back-shu and Front-mu points has solid theoretical basis and experimental evidence, and it is proved that the combination of Back-shu points and Front-mu points is effective in clinic practice. However, the mechanism study still rest on the level of spinal cord, and the breakthrough of combination of Back-Shu and Front-Mu points study is that whether the superior nerve centre involves on the regulation of zang-fu organs by combination of Back-shu and Front-mu points. The key point in future study is to explore the central control mechanism of combination of Back-shu and Front-mu points.