[Epidemiological profile of ovarian cancer]

Ginecol Obstet Mex. 2011 Sep;79(9):558-64.
[Article in Spanish]

Abstract

Background: In Mexico, ovarian cancer represents 5.3% of cancer diagnoses in all age groups and 21% of gynecologic cancers. The states with the highest incidence of this disease Nuevo León, Mexico State and Federal District.

Objective: To determine the epidemiological profile of ovarian cancer.

Patients and methods: A retrospective cross-sectional study that included all patients with complete records, diagnosed with ovarian cancer treated at the Oncology department UMAE Monterrey No. 23, January 2009 to 31 December 2009.

Results: We identified 40 patients with ovarian cancer. The average age of menarche was 12.7 years, 40% were of reproductive age, 25% were nulliparous, 15% had a pregnancy and 37.5% had two pregnancies. Of the total patients, 17% had a history of breast cancer, 40% used a contraceptive method, 37% used oral contraceptives. The tumor marker CA 125 was found in 40% of patients, 63.1% had ultrasound markers for cancer. The most frequent clinical stage 1A in which they found 32% of cases. Papillary serous adenocarcinoma was diagnosed in 25% of patients, endometroid adenocarcinoma and mucinous tumor of low malignant potential was diagnosed borderline at 20%, poorly differentiated adenocarcinoma in 18% tumor granulosa cells in 7% and papillary adenocarcinoma ring cell adenocarcinoma in 5%. In total, 43% of patients received chemotherapy.

Conclusion: The majority of cases tenia50 years or more. The background was the most frequent hereditary breast cancer. There were no deaths during the study.

Publication types

  • English Abstract

MeSH terms

  • Adenocarcinoma / drug therapy
  • Adenocarcinoma / epidemiology*
  • Adenocarcinoma / genetics
  • Adenocarcinoma / surgery
  • Adult
  • Age Factors
  • Aged
  • Biomarkers, Tumor / blood
  • Breast Neoplasms / epidemiology
  • Breast Neoplasms / genetics
  • CA-125 Antigen / blood
  • Contraception / methods
  • Contraception / statistics & numerical data
  • Cross-Sectional Studies
  • Female
  • Gastrointestinal Neoplasms / epidemiology
  • Gastrointestinal Neoplasms / genetics
  • Granulosa Cell Tumor / drug therapy
  • Granulosa Cell Tumor / epidemiology
  • Granulosa Cell Tumor / genetics
  • Granulosa Cell Tumor / surgery
  • Hormone Replacement Therapy / statistics & numerical data
  • Humans
  • Incidence
  • Mexico / epidemiology
  • Middle Aged
  • Neoplasms, Second Primary / epidemiology
  • Ovarian Neoplasms / drug therapy
  • Ovarian Neoplasms / epidemiology*
  • Ovarian Neoplasms / genetics
  • Ovarian Neoplasms / surgery
  • Parity
  • Pregnancy
  • Reproductive History
  • Retrospective Studies

Substances

  • Biomarkers, Tumor
  • CA-125 Antigen