Diagnostic performance of 64-section CT using CT gastrography in preoperative T staging of gastric cancer according to 7th edition of AJCC cancer staging manual

Eur Radiol. 2012 Mar;22(3):654-62. doi: 10.1007/s00330-011-2283-3. Epub 2011 Oct 1.

Abstract

Objectives: To evaluate the accuracy of 64-section multidetector CT with CT gastrography for determining the depth of mural invasion in patients with gastric cancer according to the 7th edition of the AJCC cancer staging manual.

Methods: A total of 127 patients with gastric cancer and who had undergone both esophago-gastro-duodenoscopy and 64-section CT were included in this study. Two radiologists independently reviewed the preoperative CT images with respect to the detectability and T-staging of the gastric cancers. The sensitivity, specificity, accuracy and overall accuracy of each reviewer for the T staging of gastric cancer were calculated.

Results: Overall, gastric cancer was detected in 123 (96.9%) of the 127 cancers on the CT images. Reviewer 1 correctly staged 98 gastric cancers, and reviewer 2 correctly classified 105 gastric cancers. The overall diagnostic accuracy of the T staging was 77.2% (98/127) for reviewer 1 and 82.7% (105/127) for reviewer 2.

Conclusion: 64-section CT using CT gastrography showed a reasonable diagnostic performance for determining the T staging in patients with gastric cancer according to the 7th edition of the AJCC cancer staging manual.

Key points: 64-section CT is useful for determining the T staging of gastric cancer Virtual gastroscopy is helpful for detecting early gastric cancer New CT criteria may be applicable to the T staging The normal gastric wall frequently shows a multilayered pattern.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Chi-Square Distribution
  • Contrast Media
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Practice Guidelines as Topic
  • Preoperative Care
  • Sensitivity and Specificity
  • Stomach Neoplasms / diagnostic imaging*
  • Stomach Neoplasms / pathology
  • Tomography, X-Ray Computed / methods*

Substances

  • Contrast Media