High hyperdiploid acute lymphoblastic leukemia in adults shows clonal heterogeneity and chromosomal instability at diagnosis and during the course of the disease

Affiliations

• ¹ Cancer Cytogenetics Unit, Medical Genetics Service, University Hospital and University of Lausanne (CHUV-UNIL), Lausanne, Switzerland.
• ² Institute of Social and Preventive Medicine, University of Lausanne, Lausanne, Switzerland.
• ³ Hematology Department, University Hospital of Basel, Basel, Switzerland.
• ⁴ Department of Hematology, University Hospital of Zurich, Zurich, Switzerland.
• ⁵ Hematology Division, University Hospital of Geneva (HUG), Geneva, Switzerland.
• ⁶ Medical Genetics Service, University Hospital and University of Lausanne (CHUV-UNIL), Av. Pierre Decker 2, CH 1011, Lausanne, Switzerland. martine.jotterand@chuv.ch.