Cytomegalovirus retinitis in an immunocompromised infant: a case report and review of the literature

Case Rep Ophthalmol. 2011 May;2(2):238-42. doi: 10.1159/000330550. Epub 2011 Aug 2.

Abstract

Purpose: To describe a case of bilateral cytomegalovirus retinitis (CMVR) in an immunocompromised infant.

Methods: A 4-month-old male infant with severe combined immunodeficiency syndrome was examined for the presence of CMVR. Ocular involvement was recorded and monitored by digital imaging.

Results: The child had bilateral CMVR, with a fine granular pattern, present both in the peripheral retina and posterior pole. There was no vitritis. The active areas of retinitis progressively resolved with intravenous ganciclovir treatment. At the 3-month follow-up examination, no recurrence was observed.

Conclusion: Ganciclovir treatment was effective in this case. The prognosis depends on rapid institution of effective antiviral therapy and on a patient's systemic immunocompetence.

Keywords: Cytomegalovirus; Ganciclovir; Infant; Retinitis.

Publication types

  • Case Reports