Clopidogrel and CYP2C19 testing: ready for clinical prime time?

Clin Chem. 2012 Jan;58(1):154-7. doi: 10.1373/clinchem.2011.165829. Epub 2011 Sep 22.
No abstract available

MeSH terms

  • Acute Coronary Syndrome / drug therapy
  • Acute Coronary Syndrome / genetics
  • Aryl Hydrocarbon Hydroxylases / genetics
  • Aryl Hydrocarbon Hydroxylases / physiology*
  • Clopidogrel
  • Cytochrome P-450 CYP2C19
  • Genetic Testing
  • Genotype
  • Heterozygote
  • Humans
  • Polymorphism, Genetic
  • Purinergic P2Y Receptor Antagonists / therapeutic use*
  • Ticlopidine / analogs & derivatives*
  • Ticlopidine / therapeutic use

Substances

  • Purinergic P2Y Receptor Antagonists
  • Clopidogrel
  • Aryl Hydrocarbon Hydroxylases
  • CYP2C19 protein, human
  • Cytochrome P-450 CYP2C19
  • Ticlopidine