Characterization of Acinetobacter baumannii from intensive care units and home care patients in Palermo, Italy

Clin Microbiol Infect. 2011 Nov;17(11):E12-5. doi: 10.1111/j.1469-0691.2011.03654.x. Epub 2011 Sep 21.

Abstract

In this study 45 isolates of Acinetobacter baumannii identified from patients in intensive care units of three different hospitals and from pressure ulcers in home care patients in Palermo, Italy, during a 3-month period in 2010, were characterized. All isolates were resistant to at least three classes of antibiotics, but susceptible to colistin and tygecycline. Forty isolates were non-susceptible to carbapenems. Eighteen and two isolates, respectively, carried the bla(OXA-23-like) and the bla(OXA-58-like) genes. One strain carried the VIM-4 gene. Six major rep-PCR subtype clusters were defined, including isolates from different hospitals or home care patients. The sequence type/pulsed field gel electrophoresis group ST2/A included 33 isolates, and ST78/B the remaining 12. ST2 clone proved to be predominant, but a frequent involvement of the ST78 clone was evident.

MeSH terms

  • Acinetobacter Infections / microbiology*
  • Acinetobacter baumannii / drug effects
  • Acinetobacter baumannii / genetics
  • Acinetobacter baumannii / isolation & purification*
  • Anti-Bacterial Agents / pharmacology
  • Cluster Analysis
  • Community-Acquired Infections / microbiology*
  • Cross Infection / microbiology*
  • Drug Resistance, Multiple, Bacterial
  • Electrophoresis, Gel, Pulsed-Field
  • Genotype
  • Home Care Services
  • Humans
  • Intensive Care Units
  • Italy
  • Microbial Sensitivity Tests
  • Molecular Typing
  • Multilocus Sequence Typing
  • beta-Lactamases / genetics

Substances

  • Anti-Bacterial Agents
  • beta-Lactamases