A prospective clinical pilot-trial comparing the effect of an optimized mixed diet versus a flexible low-glycemic index diet on nutrient intake and HbA(1c) levels in children with type 1 diabetes

J Pediatr Endocrinol Metab. 2011;24(7-8):441-7. doi: 10.1515/jpem.2011.176.

Abstract

Background: Low-glycemic index (GI) diet vs. high-GI diet improves glycemic control, but it is not clear whether a low-GI diet is superior to an optimized mixed diet (OMD).

Methods: This was a 12-week parallel-group pilot-trial including 17 children with type 1 diabetes. A separate dietary education into the allocated diet (OMD vs. low-GI) was performed. Nutrition was recorded by means of a three-day dietary record.

Objectives: The primary objective was to determine the macro- and micronutrient composition of the different diets, the secondary objective was to determine the short-term effect on HbA(1c) levels.

Results: In the low-GI group carbohydrate intake decreased, fat intake increased by trend. In the OMD group fat and energy intake decreased. No changes of HbA(1c) levels between the groups were observed.

Conclusion: OMD could have positive effects in overweight and obese diabetic children, since a reduction in fat and energy intake can be achieved. The findings of this pilot-trial suggest that OMD could be superior to a low-GI diet.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Child
  • Diabetes Mellitus, Type 1 / blood
  • Diabetes Mellitus, Type 1 / diet therapy*
  • Diabetes Mellitus, Type 1 / drug therapy
  • Diabetes Mellitus, Type 1 / psychology
  • Diet Records
  • Diet, Diabetic*
  • Dietary Carbohydrates / administration & dosage
  • Dietary Fats / administration & dosage
  • Female
  • Food Preferences / psychology
  • Germany
  • Glycated Hemoglobin / analysis*
  • Glycemic Index*
  • Humans
  • Male
  • Parents / psychology
  • Patient Education as Topic
  • Pilot Projects
  • Reproducibility of Results
  • Surveys and Questionnaires

Substances

  • Dietary Carbohydrates
  • Dietary Fats
  • Glycated Hemoglobin A
  • hemoglobin A1c protein, human