Effectiveness of Biobrane for treatment of partial-thickness burns in children

J Pediatr Surg. 2011 Sep;46(9):1759-63. doi: 10.1016/j.jpedsurg.2011.03.070.

Abstract

Purpose: Wound care for partial-thickness burns should alleviate pain, decrease hospital length of stay, and be readily applied to a variety of wounds. The effectiveness of Biobrane (UDL Laboratories, Rockford, IL) is compared with that of Beta Glucan Collagen (BGC; Brennan Medical, St. Paul, MN) in a retrospective cohort study.

Methods: A retrospective chart review of all children treated at a tertiary care pediatric hospital between 2003 and 2009 identified patients with partial-thickness burns treated with Biobrane. These patients were compared with historical controls treated with BGC.

Results: A total of 235 children between the ages of 4 weeks and 18 years with an average of 6.0% body surface area partial-thickness burns were treated with Biobrane. In a multivariate statistical analysis, patients treated with Biobrane healed significantly faster than those treated with BGC (Biobrane vs BGC: median, 9 vs 13 days; P = .019; hazard ratio, 1.68). In addition, patients who required inpatient treatment trended toward having shorter length of hospital stay in the Biobrane group (2.6 vs 4.1 days, P = .079).

Conclusion: Partial-thickness burn care consists of early debridement and application of a burn wound dressing. Biobrane dressings result in faster healing compared with BGC and may decrease hospital length of stay for patients requiring inpatient admission.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Burns / pathology
  • Burns / therapy*
  • Child
  • Child, Preschool
  • Coated Materials, Biocompatible / therapeutic use*
  • Collagen / therapeutic use*
  • Humans
  • Infant
  • Occlusive Dressings*
  • Retrospective Studies
  • Wound Healing
  • beta-Glucans / therapeutic use*

Substances

  • Biobrane
  • Coated Materials, Biocompatible
  • beta-Glucans
  • beta-glucan collagen
  • Collagen