Ginkgo biloba extract alters the binding of the sodium [123I] iodide (Na123I) on blood constituents

Appl Radiat Isot. 2012 Jan;70(1):59-62. doi: 10.1016/j.apradiso.2011.08.002. Epub 2011 Aug 18.

Abstract

We evaluated the in vitro effect of an aqueous extract of Ginkgo biloba (EGb) on the distribution in blood cells (BC) and plasma (P) and on the binding of Na(123)I to the blood constituents using precipitation with trichloroacetic acid. The radioactivity percentages insoluble (SF) and insoluble fraction (IF) of blood constituents were determined. The EGb interfered (p<0.05) on the distribution of Na(123)I in the P (from 69.64 to 86.13) and BC (from 30.36 to 13.87) and altered the fixation of the Na(123)I in IF-P and in IF-BC.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Blood Chemical Analysis / methods*
  • Blood Proteins / chemistry*
  • Ginkgo biloba / chemistry*
  • Humans
  • Iodine Radioisotopes / chemistry
  • Plant Extracts / chemistry*
  • Protein Binding
  • Protein Interaction Mapping / methods*
  • Sodium Iodide / chemistry*

Substances

  • Blood Proteins
  • Iodine Radioisotopes
  • Plant Extracts
  • Sodium Iodide