Background and objective: Most of lung cancers present with a parenchymal mass. Lung cancers that present as bullae under imaging are unusual. The aim of the current article is to raise awareness regarding bullae-associated lung cancer through two case reports and their corresponding review of literature.
Methods: The clinical, auxiliary examination data, and the diagnosis of two patients with bullae-associated lung cancer are presented and the relevant literature are reviewed.
Results: Most cases of bullae-associated lung cancer are male heavy smokers. Considering the incidence of pulmonary carcinoma associated with bullous disease is high, radiographic findings would aid in the early detection of a malignant lesion.
Conclusion: Bullous lung disease is a risk factor for lung cancer, and male, middle-age patients with bullae who smoke should be followed up by chest computed tomography and further examination. If the bullae may be diagnosed as lung cancer, an exploratory thoracotomy should be performed as early as possible.
背景与目的: 肺癌多表现为肺部实质性占位，而以肺大泡为影像学表现的肺癌较为少见。本文通过报道2例肺大泡相关性肺癌并复习相关文献，旨在提高对肺大泡相关性肺癌的认识。
方法: 本文将报道2例肺大泡相关性肺癌患者的临床表现、影像资料及诊治过程，并结合相关文献报道进行分析。
结果: 肺大泡相关性肺癌是原发性肺癌的一种特殊形式，多发生于吸烟男性，临床表现隐匿，早期较难确诊，且易被漏诊、误诊。
结论: 肺大泡患者是肺癌的高危人群，应密切进行影像随访或进一步检查，对不能排除肺癌者应积极手术治疗。