Shared and unique properties of ubiquitin and SUMO interaction networks in DNA repair

Sjoerd J L van Wijk; Stefan Müller; Ivan Dikic

doi:10.1101/gad.17593511

Shared and unique properties of ubiquitin and SUMO interaction networks in DNA repair

Genes Dev. 2011 Sep 1;25(17):1763-9. doi: 10.1101/gad.17593511.

Authors

Sjoerd J L van Wijk¹, Stefan Müller, Ivan Dikic

Affiliation

¹ Institute of Biochemistry II, Goethe University School of Medicine, 60590 Frankfurt am Main, Germany.

Abstract

In this issue of Genes & Development, Yang and colleagues (pp. 1847-1858) identify new components of a small ubiquitin-like modifier (SUMO)-like interaction network that orchestrates and fine-tunes the Fanconi anemia (FA) pathway and replication-coupled repair. This new pathway emphasizes the intricate interplay of ubiquitin (Ub) and SUMO networks in the DNA damage response.

Publication types

Comment

MeSH terms

Animals
Fanconi Anemia Complementation Group Proteins / metabolism*
Gene Expression Regulation*
Humans
Small Ubiquitin-Related Modifier Proteins / metabolism*

Substances

Fanconi Anemia Complementation Group Proteins
Small Ubiquitin-Related Modifier Proteins