Dimethylarginines in patients with type 2 diabetes mellitus: relation with the glycaemic control

Diabetes Res Clin Pract. 2011 Dec;94(3):e61-4. doi: 10.1016/j.diabres.2011.08.008. Epub 2011 Sep 1.

Abstract

We tested the relationship between plasma levels of dimethylarginines (ADMA and SDMA) and glycaemic control in 43 type 2 diabetic patients. Type 2 diabetics with poor glycaemic control (HbA1c>6.5) had significantly lower SDMA and higher ADMA concentrations than those with well-controlled glycaemia (HbA1c<6.5).

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arginine / analogs & derivatives*
  • Arginine / blood
  • Blood Glucose / analysis*
  • Case-Control Studies
  • Diabetes Complications / blood*
  • Diabetes Mellitus, Type 2 / physiopathology*
  • Female
  • Glycated Hemoglobin / analysis*
  • Glycemic Index
  • Humans
  • Male
  • Prognosis

Substances

  • Blood Glucose
  • Glycated Hemoglobin A
  • dimethylarginine
  • Arginine