Treatment of a case of mesangioproliferative glomerulonephritis secondary to Echinococcus alveolaris with albendazole

Intern Med. 2011;50(17):1821-4. doi: 10.2169/internalmedicine.50.5246. Epub 2011 Sep 1.

Abstract

Parasitic infections lead to significant morbidity and mortality, especially in tropical regions. The renal damage caused by these infections occurs via various mechanisms. Two forms of parasitic echinococcus infection widely responsible for infection in humans are Echinococcus granulosus and Echinococcus multilocularis. E. multilocularis causes Alveolar echinococcus infection in humans. Alveolar echinococcus has high mortality, and the possible limits of surgery are generally exceeded by the time of diagnosis. The literature contains no case reports of comorbidity of alveolar echinococcus and glomerulonephritis. Here we discuss the treatment of a patient with comorbid mesangioproliferative glomerulonephritis and alveolar echinococcus, behaving like a tumor, using albendazole since there was no possibility of surgery. This is the first ever such case report.

Publication types

  • Case Reports

MeSH terms

  • Albendazole / pharmacology
  • Albendazole / therapeutic use*
  • Animals
  • Echinococcosis / complications
  • Echinococcosis / diagnosis*
  • Echinococcosis / drug therapy*
  • Echinococcus / drug effects
  • Echinococcus / isolation & purification*
  • Glomerulonephritis, Membranoproliferative / diagnosis*
  • Glomerulonephritis, Membranoproliferative / drug therapy*
  • Glomerulonephritis, Membranoproliferative / etiology
  • Humans
  • Male
  • Treatment Outcome
  • Young Adult

Substances

  • Albendazole