MtbSD--a comprehensive structural database for Mycobacterium tuberculosis

Sameer Hassan; P Logambiga; A Mohan Raman; T K Subazini; V Kumaraswami; Luke Elizabeth Hanna

doi:10.1016/j.tube.2011.08.003

MtbSD--a comprehensive structural database for Mycobacterium tuberculosis

Tuberculosis (Edinb). 2011 Nov;91(6):556-62. doi: 10.1016/j.tube.2011.08.003. Epub 2011 Aug 30.

Authors

Sameer Hassan¹, P Logambiga, A Mohan Raman, T K Subazini, V Kumaraswami, Luke Elizabeth Hanna

Affiliation

¹ National Institute for Research in Tuberculosis, Chetpet, Chennai 600 031, India.

PMID: 21880546
DOI: 10.1016/j.tube.2011.08.003

Abstract

The Mycobacterium tuberculosis Structural Database (MtbSD) (http://bmi.icmr.org.in/mtbsd/MtbSD.php) is a relational database for the study of protein structures of M. tuberculosis. It currently holds information on description, reaction catalyzed and domains involved, active sites, structural homologues and similarities between bound and cognate ligands, for all the 857 protein structures that are available for M. tb proteins. The database will be a valuable resource for TB researchers to select the appropriate protein-ligand complex of a given protein for molecular modelling, docking, virtual screening and structure-based drug designing.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bacterial Proteins / chemistry*
Database Management Systems
Databases, Protein*
Drug Design
Humans
Information Storage and Retrieval
Internet
Molecular Sequence Data
Mycobacterium tuberculosis* / chemistry
Sequence Analysis, Protein / methods*
User-Computer Interface

Substances

Bacterial Proteins