The exciting discovery that dechlorinating bacteria can use polarized graphite cathodes as direct electron donors in the reductive dechlorination has prompted investigations on the development of novel bioelectrochemical remediation approaches. In this work, we investigated the performance of a bioelectrochemical reactor for the treatment of trichloroethene (TCE). The reactor was continuously operated for about 570 days, at different potentiostatically controlled cathode potentials, ranging from -250 mV to -750 mV vs standard hydrogen electrode. The rate and extent of TCE dechlorination, as well as the competition for the available electrons, were highly dependent on the set cathode potential. When the cathode was controlled at -250 mV, no abiotic hydrogen production occurred and TCE dechlorination (predominantly to cis-DCE and VC), most probably sustained via direct extracellular electron transfer, proceeded at an average rate of 15.5 ± 1.2 μmol e(-)/L d. At this cathode, potential methanogenesis was almost completely suppressed and dechlorination accounted for 94.7 ± 0.1% of the electric current (15.0 ± 0.8 μA) flowing in the system. A higher rate of TCE dechlorination (up to 64 ± 2 μmol e(-)/L d) was achieved at cathode potentials lower than -450 mV, though in the presence of a very active methanogenesis which accounted for over 60% of the electric current. Remarkably, the bioelectrochemical reactor displayed a stable and reproducible performance even without the supply of organic carbon sources with the feed, confirming long-term viability.