Clinical carbapenem-resistant Acinetobacter baylyi strain coharboring blaSIM-1 and blaOXA-23 from China

Antimicrob Agents Chemother. 2011 Nov;55(11):5347-9. doi: 10.1128/AAC.00425-11. Epub 2011 Aug 29.

Abstract

bla(SIM-1) and bla(OXA-23) were codetected in clinical carbapenem-resistant Acinetobacter baylyi strain NB09A30. Both of carbapenemase genes were located on a large plasmid (ca. 360 kb). bla(SIM-1) was found as a gene cassette inserted into a class 1 integron identical to that determined in Acinetobacter sp. isolates from South Korea. The genetic structure of bla(OXA-23) in NB09A30 was different from that in the prevalent Acinetobacter baumannii of clonal complex 92 (CC92) from the same hospital.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acinetobacter / drug effects*
  • Acinetobacter / genetics*
  • Anti-Bacterial Agents / pharmacology*
  • Bacterial Proteins / genetics*
  • Carbapenems / pharmacology*
  • Drug Resistance, Bacterial / genetics
  • Molecular Sequence Data
  • Plasmids / genetics
  • Polymerase Chain Reaction
  • beta-Lactamases / genetics*

Substances

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • Carbapenems
  • beta-Lactamases
  • carbapenemase

Associated data

  • GENBANK/JF731028
  • GENBANK/JF731029
  • GENBANK/JF731030
  • GENBANK/JF731031
  • GENBANK/JF731032
  • GENBANK/JF731033
  • GENBANK/JF731034
  • GENBANK/JF731035
  • GENBANK/JF731036
  • GENBANK/JF731037
  • GENBANK/JF731038
  • GENBANK/JF731039
  • GENBANK/JF731040