Gold-catalyzed tandem 1,3-migration/[2 + 2] cycloaddition of 1,7-enyne benzoates to azabicyclo[4.2.0]oct-5-enes

Weidong Rao; Dewi Susanti; Philip Wai Hong Chan

doi:10.1021/ja2052304

Gold-catalyzed tandem 1,3-migration/[2 + 2] cycloaddition of 1,7-enyne benzoates to azabicyclo[4.2.0]oct-5-enes

J Am Chem Soc. 2011 Oct 5;133(39):15248-51. doi: 10.1021/ja2052304. Epub 2011 Sep 14.

Authors

Weidong Rao¹, Dewi Susanti, Philip Wai Hong Chan

Affiliation

¹ Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore.

PMID: 21875135
DOI: 10.1021/ja2052304

Abstract

A synthetic method that relies on gold(I)-catalyzed tandem 1,3-migration/[2 + 2] cycloaddition of 1,7-enyne benzoates to prepare azabicyclo[4.2.0]oct-5-enes is described.