Benign metastasizing leiomyoma of the lung with malignant transformation mimicking mediastinal tumor

Masaki Ogawa; Masaki Hara; Yoshiyuki Ozawa; Satoru Moriyama; Motoki Yano; Shigeki Shimizu; Yuta Shibamoto

doi:10.1016/j.clinimag.2010.11.003

Benign metastasizing leiomyoma of the lung with malignant transformation mimicking mediastinal tumor

Clin Imaging. 2011 Sep-Oct;35(5):401-4. doi: 10.1016/j.clinimag.2010.11.003.

Authors

Masaki Ogawa¹, Masaki Hara, Yoshiyuki Ozawa, Satoru Moriyama, Motoki Yano, Shigeki Shimizu, Yuta Shibamoto

Affiliation

¹ Department of Radiology, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan. eternal@fj9.so-net.ne.jp

PMID: 21872133
DOI: 10.1016/j.clinimag.2010.11.003

Abstract

We report a rare case of benign metastasizing leiomyomas (BMLs) showing malignant transformation in one of them. A 65-year-old woman had a fever. Computed tomography (CT) revealed a mass on the left side of the anterior mediastinum and multiple nodules in bilateral lungs. The masses proved to be leiomyomas and a leiomyosarcoma. The latter showed heterogeneous contrast enhancement on CT and high heterogeneous uptake of (18)F-fluorodeoxyglucose (FDG) on positron emission tomography (PET)-CT. This case suggested the potential usefulness of PET-CT for differentiating these entities.

Publication types

Case Reports

MeSH terms

Aged
Biopsy, Needle
Female
Fluorodeoxyglucose F18
Humans
Immunohistochemistry
Leiomyoma / diagnostic imaging*
Leiomyoma / pathology*
Leiomyoma / surgery
Lung Neoplasms / diagnostic imaging*
Lung Neoplasms / secondary*
Lung Neoplasms / surgery
Multimodal Imaging
Positron-Emission Tomography
Radiopharmaceuticals
Tomography, X-Ray Computed
Uterine Neoplasms / pathology*

Substances

Radiopharmaceuticals
Fluorodeoxyglucose F18