Abstract
A case of severe diarrhoea associated with synergistic human bocavirus type 1 (HBoV) and human herpes virus type 6 (HHV6) is reported. The case supports the hypotheses that HBoV infection under clinical conditions may depend on helper viruses, or that HBoV replicates by a mechanism that is atypical for parvoviruses, or that HBoV infection can be specifically treated with cidofovir.
Publication types
-
Case Reports
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Antiviral Agents / administration & dosage
-
Antiviral Agents / therapeutic use
-
Cidofovir
-
Coinfection / diagnosis
-
Coinfection / drug therapy
-
Coinfection / pathology
-
Coinfection / virology*
-
Cytosine / administration & dosage
-
Cytosine / analogs & derivatives*
-
Cytosine / therapeutic use
-
DNA, Viral / analysis
-
Diarrhea / diagnosis
-
Diarrhea / drug therapy
-
Diarrhea / pathology
-
Diarrhea / virology*
-
Helper Viruses / drug effects
-
Helper Viruses / physiology*
-
Herpesvirus 6, Human / drug effects
-
Herpesvirus 6, Human / physiology*
-
Human bocavirus / drug effects
-
Human bocavirus / physiology*
-
Humans
-
Infant
-
Male
-
Organophosphonates / administration & dosage
-
Organophosphonates / therapeutic use*
-
Parvoviridae Infections / diagnosis
-
Parvoviridae Infections / drug therapy
-
Parvoviridae Infections / pathology
-
Parvoviridae Infections / virology*
-
Polymerase Chain Reaction
-
Roseolovirus Infections / diagnosis
-
Roseolovirus Infections / drug therapy
-
Roseolovirus Infections / pathology
-
Roseolovirus Infections / virology*
-
Viral Load / drug effects
Substances
-
Antiviral Agents
-
DNA, Viral
-
Organophosphonates
-
Cytosine
-
Cidofovir