Homozygosity for the rs9939609T allele of the FTO gene may have protective effect on becoming overweight in survivors of childhood acute lymphoblastic leukaemia

J Genet. 2011 Aug;90(2):365-8. doi: 10.1007/s12041-011-0089-3.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Alpha-Ketoglutarate-Dependent Dioxygenase FTO
  • Antineoplastic Combined Chemotherapy Protocols / adverse effects
  • Asparaginase / adverse effects
  • Child
  • Child, Preschool
  • Cyclophosphamide / adverse effects
  • Cytarabine / adverse effects
  • Daunorubicin / adverse effects
  • Female
  • Genetic Association Studies
  • Homozygote*
  • Humans
  • Male
  • Methotrexate / adverse effects
  • Obesity / etiology
  • Obesity / genetics
  • Odds Ratio
  • Overweight / etiology
  • Overweight / genetics*
  • Polymorphism, Single Nucleotide*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy
  • Prednisone / adverse effects
  • Proteins / genetics*
  • Radiotherapy / adverse effects
  • Risk Factors
  • Survivors*
  • Thioguanine / adverse effects
  • Vincristine / adverse effects
  • Young Adult

Substances

  • Proteins
  • Cytarabine
  • Vincristine
  • Cyclophosphamide
  • Alpha-Ketoglutarate-Dependent Dioxygenase FTO
  • FTO protein, human
  • Asparaginase
  • Thioguanine
  • Prednisone
  • Methotrexate
  • Daunorubicin

Supplementary concepts

  • New York protocol
  • PVDA protocol