["Common variable immunodeficiency"--first diagnosis of a rare pneumological disease]

Pneumologie. 2011 Oct;65(10):589-95. doi: 10.1055/s-0030-1256676. Epub 2011 Aug 24.
[Article in German]

Abstract

Common variable immunodeficiency (CVID) is generally used synonymously with "late onset hypogammaglobulinaemia", which is already indicative of the central pathological finding. Patients with CVID produce specifically less immunoglobulins, thus reducing their immunological competence. Our patient showed the typical medical history of undetected CVID. After excluding differential pneumological diseases, the suspected diagnosis was confirmed. This case report examines the complex of CVID as a cause for recurrent pneumological infections. It is the most prevalent form of severe antibody deficiency in children and adults and occurs with a probability of 1:25,000 in the population.

Publication types

  • Case Reports
  • English Abstract
  • Review

MeSH terms

  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Biopsy
  • Blood Protein Electrophoresis
  • Bronchoscopy
  • Common Variable Immunodeficiency / diagnosis*
  • Common Variable Immunodeficiency / drug therapy
  • Common Variable Immunodeficiency / immunology
  • Diagnosis, Differential
  • Drug Therapy, Combination
  • Follow-Up Studies
  • Giardiasis / diagnosis
  • Giardiasis / drug therapy
  • Giardiasis / immunology
  • Humans
  • Immunization, Passive
  • Lung / pathology
  • Male
  • Opportunistic Infections / diagnosis*
  • Opportunistic Infections / drug therapy
  • Opportunistic Infections / immunology
  • Pneumonia / diagnosis*
  • Pneumonia / drug therapy
  • Pneumonia / immunology
  • Splenomegaly / diagnosis
  • Splenomegaly / drug therapy
  • Splenomegaly / immunology
  • Thrombocytopenia / diagnosis
  • Thrombocytopenia / drug therapy
  • Thrombocytopenia / immunology
  • Tomography, X-Ray Computed

Substances

  • Anti-Bacterial Agents