Abstract
Comparing culture- and non-culture-based methods for quantifying Clostridium difficile in antibiotic-associated-diarrhea patients, we found that the real-time PCR method correlated well with quantitative culture and was more sensitive. A positive association between the population levels of C. difficile and the presence of its toxins was found.
Publication types
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Comparative Study
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Evaluation Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Aged
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Aged, 80 and over
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Anti-Bacterial Agents / adverse effects*
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Bacterial Load / methods*
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Bacterial Toxins / analysis
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Child
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Child, Preschool
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Clostridioides difficile / isolation & purification*
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Clostridium Infections / microbiology*
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Diarrhea / microbiology*
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Female
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Humans
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Male
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Middle Aged
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Sensitivity and Specificity
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Statistics as Topic
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Young Adult
Substances
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Anti-Bacterial Agents
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Bacterial Toxins