Magnetic resonance spectroscopy of the canine brain at 3.0 T and 7.0 T

Paula Martin-Vaquero; Ronaldo C da Costa; Rita L Echandi; Christina L Sammet; Michael V Knopp; Steffen Sammet

doi:10.1016/j.rvsc.2011.07.025

Magnetic resonance spectroscopy of the canine brain at 3.0 T and 7.0 T

Res Vet Sci. 2012 Aug;93(1):427-9. doi: 10.1016/j.rvsc.2011.07.025. Epub 2011 Aug 23.

Authors

Paula Martin-Vaquero¹, Ronaldo C da Costa, Rita L Echandi, Christina L Sammet, Michael V Knopp, Steffen Sammet

Affiliation

¹ Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Ohio State University, 601 Vernon L. Tharp Street, Columbus, OH 43210, USA. martin-vaquero.1@osu.edu

PMID: 21864873
DOI: 10.1016/j.rvsc.2011.07.025

Abstract

The purpose of this study was to evaluate the feasibility of proton magnetic resonance spectroscopy (1H MRS) to study the concentration of metabolites in the brain of dogs at 3.0 and 7.0 T. Four healthy male beagles were scanned using 3.0 T and 7.0 T human magnetic resonance imaging (MRI) units. The results obtained showed that all dogs had excellent quality spectra for a small (1 cm3) and large (8 cm3) voxel at 3.0 T, whereas only 2 dogs had high quality spectra at 7.0 T due to insufficient water suppression. 1H MRS at 3.0 T appears to be a reliable method to study metabolite concentrations in the canine brain. The development of more advanced water suppression techniques is necessary to improve the results at 7.0 T.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Brain / anatomy & histology*
Dogs / anatomy & histology
Magnetic Resonance Spectroscopy / methods*
Male
Neuroimaging / methods
Neuroimaging / veterinary*