A brief history of angiogenesis assays

Int J Dev Biol. 2011;55(4-5):377-82. doi: 10.1387/ijdb.103215ac.

Abstract

The major problem with angiogenesis research is the choice of an appropriate assay. Currently, many in vitro and in vivo techniques are available for research into the functions of endothelial cells during angiogenesis. In this historical review article, we describe and evaluate the methodology and specific features of some of the most frequently used of these assays.

Publication types

  • Historical Article
  • Portrait
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Blood Vessels / anatomy & histology
  • Blood Vessels / growth & development
  • History, 16th Century
  • History, 17th Century
  • History, 19th Century
  • History, 20th Century
  • History, 21st Century
  • History, Ancient
  • History, Medieval
  • Humans
  • Models, Animal
  • Models, Biological
  • Neovascularization, Physiologic*
  • Research / history