Plasmid-borne vga(A)-encoding gene in methicillin-resistant Staphylococcus aureus ST398 recovered from swine and a swine farmer in the United States

Rodrigo E Mendes; Tara C Smith; Lalitagauri Deshpande; Daniel J Diekema; Helio S Sader; Ronald N Jones

doi:10.1016/j.diagmicrobio.2011.06.009

Plasmid-borne vga(A)-encoding gene in methicillin-resistant Staphylococcus aureus ST398 recovered from swine and a swine farmer in the United States

Diagn Microbiol Infect Dis. 2011 Oct;71(2):177-80. doi: 10.1016/j.diagmicrobio.2011.06.009.

Authors

Rodrigo E Mendes¹, Tara C Smith, Lalitagauri Deshpande, Daniel J Diekema, Helio S Sader, Ronald N Jones

Affiliation

¹ JMI Laboratories, North Liberty, IA, USA. rodrigo-mendes@jmilabs.com

PMID: 21856108
DOI: 10.1016/j.diagmicrobio.2011.06.009

Abstract

We report a novel vga(A) detected in 3 methicillin-resistant Staphylococcus aureus ST398 recovered from swine and a swine caretaker in the United States. Strains were wild type for L3 and L4, but positive for vga(A) and tet(M). vga(A) was plasmid-located (ca. 24-kb) and demonstrated mobilization genes upstream and a transposase belonging to the IS3 family located downstream.

MeSH terms

ATP-Binding Cassette Transporters / genetics*
ATP-Binding Cassette Transporters / metabolism
Animals
Bacterial Proteins / genetics*
Bacterial Proteins / metabolism
DNA, Bacterial / genetics
Genes, Bacterial
Humans
Methicillin-Resistant Staphylococcus aureus / genetics*
Methicillin-Resistant Staphylococcus aureus / isolation & purification
Methicillin-Resistant Staphylococcus aureus / pathogenicity*
Molecular Sequence Data
Plasmids
Sequence Analysis, DNA
Swine
United States

Substances

ATP-Binding Cassette Transporters
Bacterial Proteins
DNA, Bacterial
VgA protein, Staphylococcus aureus

Associated data

GENBANK/FN546261