In recent years many studies have examined the genetic predisposition to pancreatic diseases. Pancreatic disease of an alcoholic etiology was determined to be a multi-factorial disease, where environmental factors interact with the genetic profile of the individual. In this review we discuss the main results from studies examining the frequency of genetic mutations in alcoholic chronic pancreatitis.
Keywords: alcoholism; cationic trypsinogen; chymotrypsin C; cystic fibrosis transmembrane conductance regulator; genetics; pancreatic diseases; serine protease inhibitor kazal type 1.