Structure-activity relationships of neuritogenic gentiside derivatives

ChemMedChem. 2011 Nov 4;6(11):1986-9. doi: 10.1002/cmdc.201100348. Epub 2011 Aug 10.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Benzoates / chemical synthesis*
  • Benzoates / pharmacology
  • Dose-Response Relationship, Drug
  • Drug Evaluation, Preclinical
  • Extracellular Signal-Regulated MAP Kinases / metabolism
  • Gentiana / chemistry
  • Gentisates / chemistry*
  • Gentisates / pharmacology*
  • Hydroxybenzoates / chemistry
  • Hydroxybenzoates / pharmacology
  • MAP Kinase Signaling System
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Nerve Growth Factor / pharmacology
  • Neurites / drug effects*
  • PC12 Cells
  • Phosphorylation
  • Rats
  • Structure-Activity Relationship*

Substances

  • Benzoates
  • Gentisates
  • Hydroxybenzoates
  • gentiside E
  • tetradecyl-2,3-dihydroxybenzoate
  • Nerve Growth Factor
  • Extracellular Signal-Regulated MAP Kinases