Examining the potential influence of diabetes on depression and anxiety symptoms via multiple sample confirmatory factor analysis

Ann Behav Med. 2011 Dec;42(3):341-51. doi: 10.1007/s12160-011-9298-5.

Abstract

Background: Assessing and diagnosing depression and anxiety in the presence of diabetes is complicated by overlapping symptoms that, therefore, are etiologically ambiguous (e.g., fatigue, appetite disturbance, autonomic arousal).

Purpose: The goal of the current study is to test whether overlapping symptoms are affected by the presence of diabetes by comparing structural models of symptoms in adults with and without diabetes.

Methods: Participants include 226 adults with diabetes and 380 healthy adults who completed questionnaires assessing symptoms of depression, anxiety, and health status. The most recent hemoglobin A1c lab result was obtained for diabetes patients.

Results: Multiple sample confirmatory factor analyses indicated that overlapping symptoms were strongly related to mood disturbance for adults with and without diabetes, suggesting that symptoms were not substantially influenced by diabetes.

Conclusions: It is recommended that when overlapping symptoms are present in diabetes patients, depression and anxiety should be considered as possible contributors to their presence.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Anxiety / diagnosis*
  • Anxiety / etiology
  • Anxiety / psychology
  • Case-Control Studies
  • Depression / diagnosis*
  • Depression / etiology
  • Depression / psychology
  • Diabetes Mellitus, Type 1 / complications
  • Diabetes Mellitus, Type 1 / psychology*
  • Diabetes Mellitus, Type 2 / complications
  • Diabetes Mellitus, Type 2 / psychology*
  • Factor Analysis, Statistical
  • Female
  • Glycated Hemoglobin / analysis
  • Humans
  • Iowa
  • Male
  • Middle Aged
  • Psychiatric Status Rating Scales
  • Reproducibility of Results
  • Sex Distribution
  • Socioeconomic Factors
  • Surveys and Questionnaires

Substances

  • Glycated Hemoglobin A