Abstract
Elastomeric polypeptides are very interesting biopolymers and are characterized by rubber-like elasticity, large extensibility before rupture, reversible deformation without loss of energy, and high resilience upon stretching. Their useful properties have motivated their use in a wide variety of materials and biological applications. This chapter focuses on elastin and resilin - two elastomeric biopolymers - and the recombinant polypeptides derived from them (elastin-like polypeptides and resilin-like polypeptides). This chapter also discusses the applications of these recombinant polypeptides in the fields of purification, drug delivery, and tissue engineering.
MeSH terms
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Amino Acid Sequence
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Animals
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Biocompatible Materials / chemistry*
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Biocompatible Materials / metabolism
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Chromatography, Affinity
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Delayed-Action Preparations / chemistry*
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Delayed-Action Preparations / metabolism
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Drug Carriers / chemistry*
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Drug Carriers / metabolism
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Elasticity
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Elastin / biosynthesis
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Elastin / chemistry
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Humans
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Insect Proteins / biosynthesis*
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Insect Proteins / chemistry
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Insecta
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Molecular Sequence Data
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Peptides / chemistry
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Peptides / metabolism*
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Phase Transition
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Recombinant Proteins / biosynthesis*
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Recombinant Proteins / chemistry
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Temperature
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Tissue Engineering / methods*
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Tropoelastin / biosynthesis
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Tropoelastin / chemistry
Substances
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Biocompatible Materials
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Delayed-Action Preparations
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Drug Carriers
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Insect Proteins
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Peptides
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Recombinant Proteins
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Tropoelastin
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resilin
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Elastin