Olfactory groove meningioma

Nithin D Adappa; John Y K Lee; Alexander G Chiu; James N Palmer

doi:10.1016/j.otc.2011.06.001

Olfactory groove meningioma

Otolaryngol Clin North Am. 2011 Aug;44(4):965-80, ix. doi: 10.1016/j.otc.2011.06.001.

Authors

Nithin D Adappa¹, John Y K Lee, Alexander G Chiu, James N Palmer

Affiliation

¹ Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania School of Medicine, Hospital of the University of Pennsylvania, Ravdin Building 5th Floor, 3400 Spruce Street, Philadelphia, PA 19104, USA. Nithin.Adappa@uphs.upenn.edu

PMID: 21819883
DOI: 10.1016/j.otc.2011.06.001

Abstract

Meningiomas are slow-growing benign tumors believed to originate from arachnoidal cap cells. This article discusses the surgical approaches for resection, especially the transnasal endoscopic approach. Alternative treatment options are primarily used where patients are not surgical candidates or location of recurrence precludes additional surgery. These options include radiotherapy, stereotactic radiosurgery, and chemotherapy. In addition, we discuss the current on going research in molecular targeting agents for meningioma treatment.

Publication types

Review

MeSH terms

Antineoplastic Agents / therapeutic use*
Clinical Trials as Topic
Combined Modality Therapy
Endoscopy* / adverse effects
Endoscopy* / methods
Humans
Meningeal Neoplasms / diagnosis
Meningeal Neoplasms / etiology
Meningeal Neoplasms / mortality
Meningeal Neoplasms / therapy
Meningioma / diagnosis
Meningioma / etiology
Meningioma / mortality
Meningioma / therapy*
Minimally Invasive Surgical Procedures
Molecular Targeted Therapy
Patient Selection
Radiation, Ionizing
Radiosurgery* / adverse effects
Radiosurgery* / methods
Radiotherapy*
Recurrence
Risk Factors
Survival Rate
Treatment Outcome

Substances

Antineoplastic Agents