In the title coordination compound, [Cd(C(8)H(3)NO(6))(C(5)H(8)N(3))(0.5)(H(2)O)](n), each Cd(II) atom is six-coordinated in a distorted octahedral environment surrounded by three carboxylate O atoms from two different 5-nitroisophthalate (5-NIP(2-)) ligands, two N atoms from two distinct 1,6-bis(1,2,4-triazol-1-yl)hexane (bth) ligands and one water molecule. The Cd(II) centres are bridged by the bth ligands, which lie across centres of inversion, to give a honeycomb-like two-dimensional layer structure; the layers are further connected by the bridging 5-NIP(2-) ligands with a κ(2);κ(1)-μ(2) coordination mode to generate the final three-dimensional structure. Topologically, taking the the Cd(II) atoms and the bth ligands as different four-connected nodes and the 5-NIP(2-) ligands as linkers, the three-dimensional structure can be simplified to a rare `mesh of trees' (mot) net with the Schäfli symbol (6(6))(6(4).8(2))(2).