[Nourishing-yin effect and mechanism of different parts of Cornu Elaphuri Davidiani in rats]

Zhong Yao Cai. 2011 Apr;34(4):509-11.
[Article in Chinese]

Abstract

Objective: To investigate nourishing-yin effect and mechanism of different parts of Cornu Elaphuri Davidiani in rats.

Method: The model of yin asthenia rats was built by thy roxine. The substance metabolism, pain threshold, hormone levels and biochemical indicators in serum were measured.

Results: The ethanol extract of Cornu Elaphuri Davidiani could regulate the substance metabolism and raise the pain threshold in yin asthenia model rats. Furthermore, it could regulate the hormone levels, biochemical indicators in serum and it could improvte the antioxidant ability.

Conclusion: The ethanol extract of Cornu Elaphuri Davidiani showed significant nourishing-yin effect in rats and the possible mechanism is correlated with regulating the neuroendocrine network.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adrenocorticotropic Hormone / blood
  • Animals
  • Antlers*
  • Deer*
  • Disease Models, Animal
  • Estradiol / blood
  • Ethanol / chemistry
  • Female
  • Hyperthyroidism / blood
  • Hyperthyroidism / chemically induced
  • Hyperthyroidism / drug therapy*
  • Interleukin-2 / blood
  • Male
  • Materia Medica / administration & dosage
  • Materia Medica / pharmacology*
  • Medicine, Chinese Traditional
  • Pain Threshold / drug effects
  • Random Allocation
  • Rats
  • Rats, Sprague-Dawley
  • Superoxide Dismutase / blood
  • Testosterone / blood
  • Thyroxine / adverse effects
  • Yin Deficiency / blood
  • Yin Deficiency / chemically induced
  • Yin Deficiency / drug therapy*

Substances

  • Interleukin-2
  • Materia Medica
  • Ethanol
  • Testosterone
  • Estradiol
  • Adrenocorticotropic Hormone
  • Superoxide Dismutase
  • Thyroxine