Increased RANKL and IL-6 levels might result in high bone turnover in a case of a CD34+/CD117+/myeloperoxidase(+dim) acute myeloid leukemia presenting with severe hypercalcemia and lumbar spine fractures

Leuk Res. 2011 Nov;35(11):e188-9. doi: 10.1016/j.leukres.2011.07.006. Epub 2011 Jul 29.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Aged
  • Antigens, CD34 / metabolism
  • Bone and Bones / cytology*
  • Bone and Bones / metabolism
  • Humans
  • Hypercalcemia / drug therapy
  • Hypercalcemia / etiology*
  • Hypercalcemia / pathology
  • Interleukin-6 / metabolism*
  • Leukemia, Myeloid, Acute / complications*
  • Leukemia, Myeloid, Acute / drug therapy
  • Leukemia, Myeloid, Acute / enzymology
  • Lumbar Vertebrae / drug effects
  • Lumbar Vertebrae / injuries*
  • Lumbar Vertebrae / pathology
  • Male
  • Peroxidase / metabolism*
  • Proto-Oncogene Proteins c-kit / metabolism
  • RANK Ligand / metabolism*
  • Spinal Fractures / drug therapy
  • Spinal Fractures / etiology*
  • Spinal Fractures / pathology

Substances

  • Antigens, CD34
  • Interleukin-6
  • RANK Ligand
  • Peroxidase
  • Proto-Oncogene Proteins c-kit